RNA Details
Disease Name
idiopathic pulmonary fibrosis
Tissue
lung
RNA Symbol
Lpar1
RNA ID
RNA Type
mRNA
Alteration Pattern
up regulation
Species
rattus norvegicus
Detection Methods
qRT-PCR; Mtt assay; etc.
Target
Lpa1
Pathway
NA
PubMed ID
Title
Tectorigenin inhibits the in vitro proliferation and enhances miR-338* expression of pulmonary fibroblasts in rats with idiopathic pulmonary fibrosis
Year
2010
Function
"Tectorigenin inhibits the proliferation of pulmonary fibroblasts in vitro and enhances miR-338* expression, which might in turn downregulate LPA1. This indicates a potential inhibitory role of tectorigenin on the pathogenesis of IPF"